Joan Bladé, Barcelona, Spain
Giovanni Palladini, Pavia, Italy
Amyloidosis: Classification and Epidemiology
Chair: Joan Bladé, Barcelona, Spain
Speaker: Per Westermark, Uppsala, Sweden
Giampaolo Merlini: Aiming for the Cure of Amyloid Disease
(Introduction by Robert A. Kyle)
Basic Science: Amyloid Fibril Formation, Deposition and Clearance
Chairs:
John Berk, Boston, MA, USA
Francesca Lavatelli, Pavia, Italy
Amyloid fibril structures using cryo EM and ssNMR
Marcus Fändrich, Ulm, Germany
Structural basis of amyloidogenicity
Marina Ramírez-Alvarado, Rochester, MN, USA
Drivers of amyloid organ tropism and deposition
Gunilla Westermark, Uppsala, Sweden
Tissue based diagnosis and classification of amyloidosis by mass spectrometry-based proteomics
Ahmet Dogan, New York, NY, USA
Proteotoxicity and organ damage
Francesca Lavatelli, Pavia, Italy
Intrinsec mechanisms of amyloid tissue clearance
Marianna Fontana, London, UK
Development of amyloid disruptors for ATTR amyloidosis
Mitsuharu Ueda, Kumamoto, Japan
16:30 - 16:50Discussion
A Deeper Look at ATTR-CM: An Under-recognized and Life-threatening Illness
Chair:
Pablo García-Pavía, Madrid, Spain
Mechanisms and Patterns of Cardiac Deposition in Amyloidosis
Yukio Ando, Kumamoto, Japan
Recognition and Diagnosis of ATTR Cardiomyopathy
Claudio Rapezzi, Bologna, Italy
Management of ATTR Cardiomyopathy
Pablo García-Pavía, Madrid, Spain
Panel Discussion and Q&A
AL amyloidosis: Diagnosis and Management in 2020
Chairs:
Ashutosh Wechalekar, London, UK
Stefan Schönland, Heidelberg, Germany
Diagnosis work-up and typing
Angela Dispenzieri, Rochester, MN, USA
Red-flags for early diagnosis
Ute Hegenbart, Heidelberg, Germany
New prognostic markers
Efstathios Kastritis, Athens, Greece
Cytogenetics in AL amyloidosis
Stefan Schönland, Heidelberg, Germany
Hematologic and organ response criteria
Giovanni Palladini, Pavia, Italy
19:30 - 19:50Discussion